PRP vs PRF in Los Angeles | Advanced Rejuvenation at Blue Medi Spa Sherman Oaks

PRP vs. PRF: What’s the Difference and Which Is Right for You?

At Blue Medi Spa in Sherman Oaks, many of our clients ask, “What’s the difference between PRP and PRF — and which one is better?” These regenerative therapies use your own blood to stimulate collagen, improve healing, and restore natural beauty. But while they sound similar, they work in different ways — and one may be better suited to your goals than the other. 

Let’s break it down.

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What Is PRP (Platelet-Rich Plasma)? 

PRP stands for Platelet-Rich Plasma. It's made by drawing a small amount of your blood, spinning it in a centrifuge at high speed, and extracting the yellow plasma layer rich in growth factors.

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PRP is commonly used for:

• Under-eye rejuvenation 
• Hair restoration 
• Skin texture and tone improvement
• Post-microneedling collagen boost

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It works by delivering concentrated platelets that promote healing and stimulate collagen.

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What Is PRF (Platelet-Rich Fibrin)?

PRF, or Platelet-Rich Fibrin, is the next generation of regenerative therapy. The key difference? It’s spun at a slower speed, which preserves white blood cells, stem cells, and fibrin matrix.

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This makes PRF: 

• More biologically active
• Slower-releasing (growth factors last longer in tissue)
• Thicker in texture — ideal for deeper tissue support!

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It’s often used for: 

• Tear trough (under-eye hollows)
• in combo with SkinVive or as a dermal filler alternative; 
• Scarring and skin healing support; 
• Post-laser or microneedling for faster recovery

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Which Is Better: PRP or PRF?

There’s no one-size-fits-all answer — it depends on your skin condition, treatment goals, and how quickly you want to see results.   Choose PRP if you want a fast recovery boost after microneedling or are focusing on scalp and hair. Choose PRF if you're treating delicate areas like under the eyes or want a natural volumizing effect without filler.

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Our Los Angeles-based patients love combining either PRP or PRF with Morpheus8, SkinVive, or microneedling for a deeper, longer-lasting glow.

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Why Blue Medi Spa in Sherman Oaks?

We’re one of the few medical spas in the Sherman Oaks and Los Angeles area offering both PRP and PRF — customized to your anatomy, needs, and goals. Our providers specialize in advanced regenerative therapies and stay current with the latest techniques and devices.

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Whether you’re looking to soften tired eyes, refresh your skin, or jumpstart hair growth, we’ve got the expertise and technology to deliver natural-looking results.

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Ready to Rejuvenate with PRP or PRF?

Schedule your consultation with us at Blue Medi Spa today to find out which regenerative treatment is right for you.

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Book online or call us to explore your PRP and PRF options in Sherman Oaks and beyond.

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